I exploded a tire on a single axle trailer just west of Sudbury and it went along on the wheel just fine until I got to a place I could pull over.
A business relation exploded a tire on his tri-axle trailer on the interstate and he got to a place he could pull over. The wheel was destroyed but he got over safely. All you can do it make sure all the servicable parts are looked after so they don’t fail and inspect everything else to ensure the safety of everything involved.